Human Diseases from Gain-of-Function Mutations in Disordered Protein Regions - ScienceDirect
Neurodegenerative Charcot-Marie-Tooth disease as a case study to decipher novel functions of aminoacyl-tRNA synthetases. - Abstract - Europe PMC
Endocrine diseases caused by GPCR gain-of-function mutations | Download Table
PPT - A number of diseases are caused by polyglutamine/CAG expansions. PowerPoint Presentation - ID:3311953
The consequences of loss, switch, gain or conservation of function... | Download Scientific Diagram
Gain of function mutation and inflammasome driven diseases in human and mouse models - ScienceDirect
An example of gain-of-function mutation. Most of the gene mutations... | Download Scientific Diagram
Loss-of-function genetic diseases and the concept of pharmaceutical targets | Orphanet Journal of Rare Diseases | Full Text
Loss-of-function, gain-of-function and dominant-negative mutations have profoundly different effects on protein structure | Nature Communications
4 Potential Benefits of Gain-of-Function Research | Potential Risks and Benefits of Gain-of-Function Research: Summary of a Workshop | The National Academies Press
Loss-of-function, gain-of-function and dominant-negative mutations have profoundly different effects on protein structure: implications for variant effect prediction | bioRxiv
Mechanisms conferring protein loss and toxic gain-of-function effects.... | Download Scientific Diagram
Gain-of-Function Mutations: An Emerging Advantage for Cancer Biology: Trends in Biochemical Sciences
Top targetable diseases due to gain-of-function mutations | Download Table
Patterns of Inheritance - Session 2 - ppt video online download
Gain-of-function research is more than just tweaking risky viruses – it's a routine and essential tool in all biology research
STAT6 gain-of-function variant exacerbates multiple allergic symptoms - ScienceDirect
Molecular basis of genetic diseases. Effects of loss-and... | Download Scientific Diagram
Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6
What is “gain-of-function” research?
Gain-of-Function Research: Summary of the Second Symposium, March 10-11, 2016 | The National Academies Press
